Spravato® Treatment in Miramar A New Path Forward for Treatment-Resistant Depression

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A Different Approach to Depression That Won't Respond

At South Florida Med Group, we understand the exhaustion that comes with treatment-resistant depression. You've tried medication after medication. You've given each one time. You've done everything right and still, the weight remains.

Spravato® represents a fundamentally different approach. Unlike traditional antidepressants that take weeks to work, Spravato® acts on different brain pathways and can bring relief more rapidly for those who haven't found success with standard treatments.

We recognize that no two patients are alike. That's why we offer Spravato® as part of a comprehensive treatment plan that may include medication management, therapy coordination, and ongoing psychiatric support all built around your needs, your story, and your goals.

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"In Miramar, we see how exhausting ongoing depression can be. Spravato® offers a new direction for those who haven’t found relief. Our clinical team walks with you every step—with consistency, empathy, and results-driven care."

– Stephanie M. Cabrera, PMHNP-BC, FNP-BC

What Is Spravato®?

Spravato® (esketamine) is an FDA-approved nasal spray used in combination with an oral antidepressant for adults (18 years and older) with:

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You've tried at least two different antidepressants without adequate improvement

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When depression reaches a crisis point requiring immediate intervention

How Spravato® Works Differently

Man self administering a 28 mg Spravato nasal spray during Spravato treatment in Miami Lakes

Traditional antidepressants work on serotonin, norepinephrine, or dopamine systems and can take 4-8 weeks to show benefits. Spravato® works through a different mechanism targeting NMDA receptors in the brain and some patients experience improvement in depressive symptoms within hours to days.

What to Expect During Treatment

Spravato® is administered as a nasal spray under direct medical supervision at our Miami Lakes clinic. You'll remain in our comfortable office for at least two hours after each dose while our team monitors your response and ensures your safety.

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Induction Phase (Weeks 1-4)

Twice weekly sessions

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Maintenance Phase

Once weekly or every other week, based on your response

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Each Session

Approximately 2-3 hours including observation time

Spravato® is always used alongside an oral antidepressant as part of a comprehensive treatment approach.

Who Is a Candidate for Spravato®?

you May Be a Candidate If:
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You're an adult (18 years or older) diagnosed with Major Depressive Disorder (MDD)

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You've tried at least two different antidepressants without
adequate relief

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Your depression significantly impacts your daily functioning and
quality of life

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You're looking for an innovative, evidence-based treatment option

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You can commit to in-office treatment sessions with
post-dose monitoring

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You have transportation available after treatment (you cannot
drive for 24 hours after dosing)

Important Safety Considerations

Spravato® requires a Risk Evaluation and Mitigation Strategy (REMS) program due to risks of sedation, dissociation, and potential for misuse. All treatments are administered in our certified clinic under direct medical supervision. Patients must be monitored for at least 2 hours after each dose and cannot drive or operate machinery for the remainder of the treatment day.

Not appropriate for patients with:
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History of aneurysmal vascular disease or arteriovenous malformation

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History of intracerebral hemorrhage

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Hypersensitivity to esketamine, ketamine, or any excipients

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Need help?

Schedule your first visit today

Insurance Coverage & Financial Accessibility

Spravato® is covered by Medicare and most major commercial insurance plans for FDA-approved indications. Coverage typically includes the medication cost and administration/monitoring fees when prior authorization is approved.

Preferred Care Partners insurance logo accepted for mental health and primary care in Miami Lakes
Preferred Care Network insurance logo accepted for mental health and primary care in Miami Lakes
Medicare logo for coverage accepted at South Florida Med Group in Miami Lakes FL
Cigna insurance logo accepted for mental health and primary care visits in Miami Lakes
TRICARE insurance logo accepted for mental health and primary care visits in Miami Lakes
Florida Blue insurance logo accepted for mental health and primary care visits in Miami Lakes
Aetna insurance logo accepted for mental health and primary care visits in Miami Lakes
Curative insurance logo accepted for mental health and primary care visits in Miami Lakes
Oscar Health insurance logo accepted for mental health and primary care visits in Miami Lakes
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Your Journey Starts with Three Steps

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Our Spravato® Treatment
Approach

step-1
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Schedule a
Personalized Consultation

Begin with a full psychiatric assessment to determine if Spravato® is right for you. Our team reviews your mental health history, past treatments, medications, and goals to create a clear path forward.

step-2
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Get a Personalized Plan & Insurance Support

If you're a good candidate, we develop a customized treatment plan and handle all insurance steps including prior authorization, benefit checks, and scheduling so your care is seamless from
the start.

step-3
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Begin Supervised
In-Office Treatment

Your Spravato® sessions take place in a private, comfortable setting. You'll self-administer the nasal spray under direct supervision, followed by monitored rest and ongoing treatment adjustments to support your long-term progress.

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Why Choose South Florida Med Group for Spravato® Treatment

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REMS-Certified Treatment Facility

Our clinic is fully certified through the Spravato® REMS program, meeting all FDA safety requirements for administration and monitoring. Your safety is our highest priority.

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Board-Certified Psychiatric Expertise

Stephanie Cabrera, MSN, NP-C, is double board-certified (AANP & ANCC) with specialized training in treatment-resistant depression and advanced psychiatric interventions. You're in expert hands.

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Compassionate, Faith-Centered Care

We treat the whole person mind, body, and spirit. Our approach honors your values and supports healing through evidence-based medicine delivered with genuine compassion.

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Insurance Navigation & Financial Support

We accept most major insurance plans and handle all prior authorization paperwork. Our team works to verify your Spravato® coverage and connect you with patient assistance programs when needed.

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Convenient Miami Lakes Location

Located at 16969 NW 67th Avenue, Suite 205, our clinic serves adult patients throughout Miami-Dade County, including Hialeah, Miami Gardens, Doral, Aventura, and surrounding communities.

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Integrated Mental Health Services

Beyond Spravato®, we offer comprehensive adult psychiatric care including medication management, TMS therapy for depression, and coordination with psychotherapy providers—creating a complete support system for your recovery.

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Testimonials

Care That Makes a Difference

Hear from people whose lives have been transformed through our support.

Melissa T.

Five star rating from a South Florida Med Group patient in Miami Lakes

"Before coming to South Florida Med Group, I lived in a constant state of tension—my heart was always racing, my thoughts never stopped. I was functioning on the outside but falling apart inside. The team here helped me understand the root of my anxiety and gave me real tools to work through it. Now, I sleep better, think clearer, and finally feel present in my own life again."

Darren C.

Five star rating from a South Florida Med Group patient in Miami Lakes

"I used to feel like I was drowning in my own thoughts. Simple things like answering emails or going to the grocery store would send me spiraling. South Florida Med Group gave me more than just coping skills—they gave me back my peace of mind. Their holistic approach, including therapy and spiritual support, made a bigger impact than I ever expected."

Natalie F.

Five star rating from a South Florida Med Group patient in Miami Lakes

"Anxiety for me was this quiet weight I carried every day. I looked fine, but inside, I felt like I was constantly failing. Coming here was the first time I felt seen and understood. My provider didn’t rush me or brush off what I was feeling. Instead, they helped me create a step-by-step plan that actually worked. I’m not just surviving anymore—I’m living with intention."

Eric W.

Five star rating from a South Florida Med Group patient in Miami Lakes

"I had been praying for something to help with my anxiety, and this clinic was the answer. I never thought I’d be someone who could go out without checking every exit or overthinking every conversation. With their support, I’ve learned how to manage my triggers and stay grounded. My relationships are better, and so is my faith in myself."

Jasmine H.

Five star rating from a South Florida Med Group patient in Miami Lakes

"Every day felt like walking on eggshells around my own emotions. I didn’t even realize how much it was affecting my marriage and my work. From the first consultation, I felt like I was in the right place. They were kind, patient, and really helped me understand how anxiety works in the body and the mind. That understanding gave me the confidence to take control again."

Luis R.

Five star rating from a South Florida Med Group patient in Miami Lakes

"I’ve struggled with anxiety since I was a teenager, and most places just gave me prescriptions and sent me on my way. At South Florida Med Group, the care went deeper. They took time to understand my story and helped me rebuild my routine, my mindset, and even my spiritual focus. I’m still healing, but I finally feel like I’m on solid ground."

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Feel Better.

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Live Brighter.

Take the first step toward peace of mind and lasting well-being—because you matter. We're here to listen, guide, and help you move forward with care.

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FAQ’s

Frequently Asked Questions?

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How quickly does Spravato® work?

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Some patients experience improvement in depressive symptoms within hours to days after their first dose, though individual responses vary. Unlike traditional antidepressants that take 4-8 weeks, Spravato® works through a different brain mechanism that may produce more rapid effects. Your treatment team will monitor your progress closely during the induction phase.

What does Spravato® treatment feel like?

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During and after administration, you may experience dissociation (feeling detached from reality), dizziness, sedation, or changes in perception. These effects typically resolve within 1.5-2 hours, which is why you remain under medical observation. Most patients find the experience manageable, especially in our supportive clinical environment.

Can I drive after my Spravato® session?

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No. You cannot drive or operate machinery for at least 24 hours after receiving Spravato®. You must arrange for someone to drive you home after each treatment session. This is a critical safety requirement.

How long will I need Spravato® treatment?

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Treatment duration is individualized. Most patients begin with twice-weekly sessions for 4 weeks (induction phase), then transition to weekly or every-other-week maintenance dosing based on their response. Some patients continue treatment long-term to maintain improvement, while others may eventually taper off under medical guidance.

Is Spravato® addictive?

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Spravato® has a potential for misuse and dependence, which is why it's only available through the REMS program with administration in certified healthcare settings under direct supervision. You cannot take Spravato® home. All dosing occurs in our clinic with mandatory monitoring.

Will I still need my antidepressant medication?

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Yes. Spravato® is always used in combination with an oral antidepressant. It's not a replacement for your current medication—it's an augmentation strategy designed to enhance treatment response.

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